| Product dosage: 20mg | |||
|---|---|---|---|
| Package (num) | Per pill | Price | Buy |
| 60 | $0.72 | $43.04 (0%) | 🛒 Add to cart |
| 90 | $0.67 | $64.56 $60.05 (7%) | 🛒 Add to cart |
| 120 | $0.63 | $86.08 $76.07 (12%) | 🛒 Add to cart |
| 180 | $0.61 | $129.12 $109.10 (16%) | 🛒 Add to cart |
| 270 | $0.59 | $193.67 $159.14 (18%) | 🛒 Add to cart |
| 360 | $0.58
Best per pill | $258.23 $209.19 (19%) | 🛒 Add to cart |
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tamoxifen
Tamoxifen citrate represents one of those fascinating molecules that somehow manages to be both incredibly straightforward in its primary mechanism yet remarkably complex in its clinical behavior. As a selective estrogen receptor modulator (SERM), it’s been our frontline weapon against hormone receptor-positive breast cancer for decades now, but what continues to surprise me after all these years is how much we’re still learning about its nuances. The way this compound can act as an antagonist in breast tissue while functioning as an agonist in other systems like bone and endometrium creates this therapeutic tightrope we walk with every prescription.
arimidex
Anastrozole, marketed under the brand name Arimidex, represents a cornerstone in endocrine therapy for hormone receptor-positive breast cancer. As a non-steroidal aromatase inhibitor, it specifically targets the aromatase enzyme responsible for converting androgens into estrogens in peripheral tissues—the primary source of estrogen in postmenopausal women. This mechanism provides a targeted approach to reducing estrogen levels without the androgenic side effects associated with earlier therapies like aminoglutethimide. The development of selective aromatase inhibitors like anastrozole marked a significant advancement over previous generation drugs, offering improved specificity and tolerability while maintaining potent estrogen suppression.
aromasin
Aromasin, known generically as exemestane, is a steroidal aromatase inactivator used primarily in postmenopausal women with hormone receptor-positive early and advanced breast cancer. Unlike earlier anti-estrogen therapies that competed for receptor sites, Aromasin permanently binds to the aromatase enzyme, shutting down estrogen production in peripheral tissues—the primary source in postmenopausal women. We initially viewed it as just another aromatase inhibitor, but its irreversible binding mechanism and steroidal structure created unique clinical advantages we didn’t fully appreciate until working with hundreds of patients.
Evista: Bone Density Preservation and Breast Cancer Risk Reduction - Evidence-Based Review
Evista, known generically as raloxifene hydrochloride, represents a significant class of therapeutic agents in women’s health. It’s a selective estrogen receptor modulator (SERM) approved for the prevention and treatment of osteoporosis in postmenopausal women and for the reduction in risk of invasive breast cancer in postmenopausal women with osteoporosis or at high risk for invasive breast cancer. Its unique mechanism allows it to act as an estrogen agonist on bone and lipid metabolism while acting as an estrogen antagonist on breast and uterine tissue.
Femara: Potent Estrogen Suppression for Breast Cancer - Evidence-Based Review
Letrozole, marketed under the brand name Femara among others, is an oral non-steroidal aromatase inhibitor that has fundamentally changed the treatment landscape for hormone receptor-positive breast cancer in postmenopausal women. It works by selectively inhibiting the aromatase enzyme, which is responsible for the final step in estrogen synthesis, thereby dramatically reducing circulating estrogen levels in the body. This makes it a cornerstone of endocrine therapy for a disease that affects millions worldwide.
fertomid
Fertomid represents one of those interesting cases where a well-established pharmaceutical agent gets repurposed into the supplement space, creating both opportunities and significant clinical questions. As a reproductive endocrinologist who’s prescribed this medication in various forms for nearly two decades, I’ve watched this transition with both curiosity and concern. The core molecule—clomiphene citrate—has been around since the 1960s, originally developed as a fertility treatment. What’s fascinating about Fertomid’s current iteration is how it’s positioned for broader hormonal balancing applications beyond just ovulation induction.
fluoxetine
Fluoxetine, a selective serotonin reuptake inhibitor (SSRI), represents one of the most widely prescribed antidepressants globally. Marketed under brand names like Prozac, this compound has fundamentally altered psychiatric treatment paradigms since its introduction in the late 1980s. Unlike earlier tricyclic antidepressants, fluoxetine offered a more favorable side effect profile while maintaining robust efficacy for major depressive disorder. Its mechanism—selectively blocking serotonin reuptake in synaptic clefts—creates a gradual neuromodulatory effect that distinguishes it from immediate-acting psychotropics.
hydroxychloroquine
Hydroxychloroquine sulfate, an antimalarial and immunomodulatory agent derived from quinine, exists as a white crystalline powder with molecular formula C18H26ClN3O and molecular weight 335.872 g/mol. The compound’s distinctive chemical structure features a 4-aminoquinoline backbone with a hydroxyethyl side chain at the 7-position, which significantly reduces ocular toxicity compared to its parent compound chloroquine while maintaining therapeutic efficacy. Available as 200mg film-coated tablets equivalent to 155mg base, this disease-modifying antirheumatic drug (DMARD) demonstrates remarkable pH-dependent accumulation in lysosomes, achieving concentrations 100-1000 times higher than extracellular levels - a pharmacokinetic property central to its mechanism across multiple indications.
Nolvadex: Estrogen Receptor Modulation for Breast Cancer and Beyond - Evidence-Based Review
Nolvadex, known generically as tamoxifen citrate, is a selective estrogen receptor modulator (SERM) with a well-established role in oncology and specialized endocrine applications. Originally developed in the 1960s, its primary mechanism involves competitively blocking estrogen receptors in certain tissues, notably breast tissue, while acting as a partial agonist in others like bone and endometrium. This dual activity makes it particularly valuable for hormone-sensitive conditions. Available typically in 10 mg or 20 mg oral tablets, Nolvadex requires careful clinical oversight due to its potent systemic effects and significant drug interaction profile.